
Living with Anxiety (LwA) study digital media kit
FOR IMMEDIATE USE, TUESDAY, MARCH 18, 2025

MEDIA ALERT
FOR IMMEDIATE USE, TUESDAY, MARCH 18, 2025
Unravelling the genetic code of anxiety disorders
AUS researchers seeking 5,000 adults diagnosed with anxiety
for groundbreaking ‘Living with Anxiety’ genetics study
Aussie researchers will call for 5,000 adult (18+ years)
volunteers diagnosed with, or treated for an anxiety
disorder, for their groundbreaking Living with Anxiety
(LwA) study today (Tuesday, March 18, 2025).
The LwA study aims to identify genes that influence a
person’s risk of developing anxiety, and response to
treatment, with the goal of improving diagnosis,
management and treatment.
The researchers’ appeal for volunteers will coincide
with the publication of their article in MJA Insight+,
explaining how the LwA study is promising to pave the way toward more personalised and optimised anxiety disorder treatments.1
Anxiety disorders:
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affect 3.4 million Australians aged 16-85 years each year;1
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represent the nation’s most common mental health condition;1
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present in various forms;2
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are often associated with other conditions, such as depression;1
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can significantly compromise daily functioning and overall wellbeing;1, 3-5
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and depressive disorders are among the most common reasons patients visit their GP.6
While psychological therapies are usually the first, and most effective treatment option7 for these
life-disrupting anxiety disorders,8 medication is also commonly prescribed. Finding the right medication can, however, prove time-consuming and complex.9
Around one-in-five people who take medication for their anxiety experience distressing side-effects,10 which often leads to treatment cessation,11 while up to 65 per cent may fail to respond to prescribed treatments due to their genetic make-up.12
Large scale studies like the LwA study are crucial for advancing the science of how our DNA influences medication responses.13
Unravelling the genetics of anxiety disorders will enable the development of new, and more effective, personalised treatments, better able to target the problem directly.
To learn more about the LwA study and the MJA Insight+ article, tee up an interview with a spokesperson overleaf.
To volunteer for the Living with Anxiety (LwA) study, head to livingwithanxiety.org.au or email lwa@qimrb.edu.au.

AVAILABLE FOR INTERVIEW
EXPERTS
Prof Sarah Medland, OAM
Lead Investigator, Living with Anxiety (LwA) study & Head of
Psychiatric Genetics Group, QIMR Berghofer, BRISBANE
Prof Nick Martin
Co-Investigator, Living with Anxiety (LwA) study & Head, Genetic Epidemiology, QIMR Berghofer, BRISBANE
Prof Ian Hickie, AO
Co-Investigator, Living with Anxiety (LwA) study; Professor of Psychiatry & Co-Director, Health & Policy, Brain & Mind Centre, The University of Sydney, SYDNEY
A/Prof Elizabeth Scott
Co-Investigator, Living with Anxiety (LwA) study; Principal Research Fellow & Academic Lead, Brain & Mind Centre, The University of Sydney, SYDNEY
Prof Malcolm Hopwood
Chair of Psychiatry, Ramsay Health Care & Professor of Psychiatry, University of Melbourne, MELBOURNE
Prof Sarah Cohen-Woods
Professor of Psychology, Flinders University Institute for Mental Health and Wellbeing & Head of the Behavioural Genetic & Environmental Mechanisms Lab, Flinders University, ADELAIDE
Prof Sean Hood
Consultant Psychiatrist at Sir Charles Gairder Hospital; & The Marian Centre, Wembley, Psychiatrist Academic at the University of Western Australia; & Head of the UWA Division of Psychiatry, PERTH
PATIENT ADVOCACY REPRESENTATIVE
Georgie Harman
Chief Executive Officer, Beyond Blue, MELBOURNE
AUSTRALIANS LIVING WITH ANXIETY
Krish, 26
Small business owner and outdoors enthusiast who changed her lifestyle to better manage her anxiety, BLUE MOUNTAINS
Alexis, 34
Lived Experience Research who has faced anxiety for many years, SYDNEY
Rachael, 52
Former police officer turned children’s author, has lived with feelings of anxiety since the tender age of 10, NEWCASTLE
Melanie, 37
Operations administrator who has lived with feelings of anxiety since childhood, MELBOURNE
Liv, 37
Romance author who was diagnosed with generalised anxiety a decade ago, MELBOURNE
Mary, 43
Mother-to-one, wife & legal operations consultant who lives with
anxiety and depression, MELBOURNE
Fiona, 41
Office administrator & mother-to-three has grappled with feelings of anxiety from childhood, BRISBANE
Camille, 33
Workplace consultant who has defied a lifelong battle with anxiety, now empowering others to overcome their own mental health challenges, SUNSHINE COAST
Sean, 49
Health and safety officer and former police officer who silently endured symptoms of anxiety for many years, TASMANIA
Janine, 49
Public servant living with symptoms of anxiety since her teens, ADELAIDE
James, 49
Web developer who has battled feelings of anxiety for most of his life, PERTH
Should you suspect that you, or a loved one, may be living with anxiety, speak to your local healthcare practitioner without delay.
Australian professional patient support services offering 24/7 helpline services include:
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Beyond Blue: 1300 22 4636
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Lifeline: 13 11 14
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MensLine: 1300 78 9978
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MindSpot Clinic: 1800 61 4434
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SANE Australia: 1800 18 7263
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Headspace on 1800 650 890.
References
1. National Study of Mental Health and Wellbeing [Internet]. Canberra: ABS: Australian Bureau of Statistics; 2023 [Available from: https://www.abs.gov.au/statistics/health/mental-health/national-study-mental-health-and-wellbeing/latest-release.].
2. Anxiety disorders: National Institute of Mental Health (NIMH); [Available from: https://www.nimh.nih.gov/health/topics/anxiety-disorders].
3. Anxiety: healthdirect; 2024 [Available from: https://www.healthdirect.gov.au/anxiety].
4. Kvaal K, McDougall FA, Brayne C, Matthews FE, Dewey ME. Co-occurrence of anxiety and depressive disorders in a community sample of older people: results from the MRC CFAS (Medical Research Council Cognitive Function and Ageing Study). Int J Geriatr Psychiatry. 2008;23(3):229-37.
5. American Psychiatric A. Diagnostic and statistical manual of mental disorders: DSM-5-TR. Fifth edition, text revision. ed. Washington, DC: American Psychiatric Association Publishing; 2022.
6. General Practice - Health of the Nation - An annual insight into the state of Australian general practice: RACGP; 2024 [Available from: https://www.racgp.org.au/general-practice-health-of-the-nation.
7. Anxiety Treatment: Black Dog Institute; [Available from: https://www.blackdoginstitute.org.au/resources-support/anxiety/treatment/.
8. Anxiety Disorders: National Institutes of Mental Health; [Available from: https://www.nimh.nih.gov/health/topics/anxiety-disorders#:~:text=Anxiety%20disorder%20symptoms%20can%20interfere,refuse%20to%20leave%20their%20home.
9. Antidepressants: healthdirect; [Available from: https://www.healthdirect.gov.au/antidepressants#:~:text=headaches%20and%20dizziness,also%20known%20as%20serotonin%20syndrome).
10. Whooley MA, Simon GE. Managing depression in medical outpatients. N Engl J Med. 2000;343(26):1942-50.
11. Kopcalic K, Arcaro J, Pinto A, Ali S, Barbui C, Curatoli C, et al. Antidepressants versus placebo for generalised anxiety disorder (GAD). Cochrane Database Syst Rev. 2025;1(1):Cd012942.
12. Krebs K, Milani L. Translating pharmacogenomics into clinical decisions: do not let the perfect be the enemy of the good. Human Genomics. 2019;13(1):39.
13. Genomics and Your Health - Pharmacogenomics: CDC [Available from: https://www.cdc.gov/genomics-and-health/pharmacogenomics/index.html.